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Key Facts
- Drug Class
- Beta-lactam antibiotic
- Prescription
- Required
- NAFDAC Status
- NAFDAC Registered
- Forms
- Capsule, Suspension, Dispersible tablet
- Price Range
- ₦350 - ₦4,000
- WHO Essential
- Yes
What is Amoxicillin?
Amoxicillin is the most widely used antibiotic in Nigeria and across West Africa. It belongs to the penicillin family of antibiotics, which are part of a larger group known as beta-lactam antibiotics. Amoxicillin works by interfering with the ability of bacteria to form cell walls, which ultimately kills the bacteria. It is effective against a wide range of both gram-positive and gram-negative bacteria, making it a first-line treatment for many common infections seen in Nigerian hospitals, clinics, and health centres.
In Nigeria, amoxicillin is available under several brand names including Amoxil, Gramox, and Inamox, and can be found in virtually every pharmacy and patent medicine store across the country. It comes as capsules (250mg and 500mg), oral suspension for children, and dispersible tablets. The suspension form is especially important for paediatric use, as childhood infections such as ear infections, throat infections, and chest infections are extremely common in Nigeria's tropical climate.
One major concern with amoxicillin use in Nigeria is the growing problem of antibiotic resistance driven by self-medication. Many Nigerians purchase amoxicillin over the counter without a prescription, often taking incomplete courses or using it for viral infections like colds and malaria where antibiotics are ineffective. This misuse has contributed to rising resistance rates, making previously treatable infections harder to manage. The National Agency for Food and Drug Administration and Control (NAFDAC) and health authorities continue to advocate for responsible antibiotic use to preserve the effectiveness of this essential medicine.
What is Amoxicillin used for?
In Nigeria, Amoxicillin is commonly used for:
- Urinary tract infections (UTIs) — a very common complaint at Nigerian hospitals and clinics
- Upper and lower respiratory tract infections including bronchitis and pneumonia
- Ear infections (otitis media), especially in children
- Dental infections and abscesses
- Typhoid fever — usually in combination with other antibiotics
- Skin and soft tissue infections
- Throat infections including streptococcal pharyngitis (strep throat)
- Helicobacter pylori eradication (as part of triple therapy for peptic ulcer disease)
Dosage
IMPORTANT
Always follow your doctor's or pharmacist's instructions. The information below is for general reference only.
Adults
The standard adult dose is 500mg taken three times daily (every 8 hours) for 5 to 7 days. For milder infections, 250mg three times daily may be sufficient. The capsules should be swallowed whole with a full glass of water and can be taken with or without food. It is essential to complete the full course of treatment even if you start feeling better, to prevent antibiotic resistance.
Children
Dosage for children is based on body weight. The usual dose is 25mg to 50mg per kilogram of body weight per day, divided into three doses (every 8 hours). For children who cannot swallow capsules, amoxicillin suspension is available in 125mg/5ml and 250mg/5ml strengths. Your pharmacist will help measure the correct dose using the child's weight. Always use the measuring spoon or syringe provided — do not use household spoons.
Elderly
Elderly patients generally take the same dose as adults, but your doctor may adjust the dose if there is reduced kidney function. Kidney function tests may be recommended for elderly patients on prolonged courses.
Always complete the full course of antibiotics as prescribed. Do not share your medication with others, even if they have similar symptoms. Store suspension in the refrigerator after reconstitution and discard after 14 days. If you miss a dose, take it as soon as you remember, but do not double up on your next dose.
Side Effects
Common side effects
- •Diarrhoea — this is the most frequently reported side effect
- •Nausea and vomiting
- •Skin rash
- •Stomach discomfort or abdominal pain
- •Headache
Serious side effects — seek medical help immediately
- Severe allergic reaction (anaphylaxis) — symptoms include difficulty breathing, swelling of the face, lips, or throat, and severe skin rash. This is a medical emergency.
- Stevens-Johnson syndrome — a rare but serious skin reaction with blistering and peeling
- Clostridium difficile-associated diarrhoea — severe, watery diarrhoea that does not stop
- Liver problems — yellowing of the skin or eyes (jaundice), dark urine
- Blood disorders — unusual bruising, bleeding, or persistent sore throat
When to see a doctor
Seek immediate medical attention if you develop difficulty breathing, severe swelling, widespread rash with blistering, severe diarrhoea with blood, or yellowing of the skin. In Nigeria, go to the nearest hospital emergency unit or call your doctor immediately. If you are in a rural area, visit the nearest primary health centre. Do not wait for symptoms to worsen — allergic reactions to penicillins can be life-threatening.
Warnings & Precautions
Do not take Amoxicillin if you have:
- Known allergy to penicillin or any other beta-lactam antibiotic (such as ampicillin or amoxicillin-clavulanate)
- Previous severe allergic reaction (anaphylaxis) to any penicillin-type antibiotic
- History of liver problems associated with amoxicillin use
- Infectious mononucleosis (amoxicillin can cause a distinctive rash in this condition)
Drug interactions
- •Methotrexate — amoxicillin can increase methotrexate toxicity
- •Warfarin — may increase the anticoagulant effect, requiring closer monitoring of INR
- •Oral contraceptive pills — although evidence is debated, some clinicians advise using additional contraception during antibiotic treatment
- •Probenecid — increases amoxicillin blood levels by reducing kidney excretion
- •Allopurinol — increased risk of skin rash when taken together
Pregnancy & Breastfeeding
Amoxicillin is generally considered safe for use during pregnancy and breastfeeding. It is classified as Category B in pregnancy, meaning animal studies have shown no risk, and it is widely prescribed for pregnant women in Nigeria for conditions like UTIs and respiratory infections. Small amounts pass into breast milk but are not usually harmful to the nursing infant. However, always consult your doctor or pharmacist before taking any medication during pregnancy or while breastfeeding.
NAFDAC-Registered Brands of Amoxicillin in Nigeria
5 brands registered with NAFDAC as of 2026-02-01.
| Brand Name | Manufacturer | Strength | Form | NAFDAC Reg. No. |
|---|---|---|---|---|
| Amoxil | GlaxoSmithKline | 250mg, 500mg | Capsule | A4-0123 |
| Amoxicillin | Emzor | 500mg | Capsule | A4-5678 |
| Amoxil Suspension | GSK | 125mg/5ml, 250mg/5ml | Suspension | A4-0124 |
| Inamox | Intas | 500mg | Capsule | B4-1290 |
| Gramox | Fidson | 250mg, 500mg | Capsule | A4-4521 |
How to Verify Your Amoxicillin is Genuine
- 1Check the NAFDAC registration number printed on the packaging. All genuine medicines sold in Nigeria must carry a valid NAFDAC number.
- 2Use the NAFDAC Mobile Authentication Service (MAS): scratch the panel on the product packaging and send the code via SMS to 38353 to verify authenticity.
- 3Buy from reputable pharmacies rather than open markets or roadside vendors. Registered pharmacies are more likely to stock genuine products.
- 4Check the expiry date and ensure the packaging is intact with no signs of tampering.
- 5Look for the manufacturer's hologram or security features on the pack if available.
- 6If the price seems unusually cheap compared to market rates (below ₦350 for a standard pack), be cautious — it may be substandard or counterfeit.
Amoxicillin Price in Nigeria
Amoxicillin prices in Nigeria typically range from ₦350 to ₦4,000 per pack, depending on the brand, strength, and where you buy it.
₦350 – ₦4,000
per pack
Prices vary by location and vendor. Last updated: 2026-02-01
Where to Buy
Purchase Amoxicillin only from licensed pharmacies and verified distributors. Avoid buying medicines from unverified sources, roadside vendors, or unregistered market stalls.
Frequently Asked Questions
Sources
- •NAFDAC Greenbook — National Agency for Food and Drug Administration and Control registered products database
- •WHO Model List of Essential Medicines (23rd List, 2023)
- •British National Formulary (BNF)
- •Nigerian Standard Treatment Guidelines